The concept of 'Mirror Life,' which involves using mirror images of biological molecules to create mirror bacteria, is drawing significant attention in the world of biotechnology. While this innovative approach offers new possibilities, experts are also warning of considerable biosecurity risks.

Mirror bacteria, or chiral bacteria, are composed of mirrored molecules. While some molecules naturally exist as mirror images—such as DNA with right-handed nucleotides and proteins with left-handed amino acids—it is currently not possible to fully create mirror bacteria. However, advancements in biotechnology are progressing rapidly. Curiosity, alongside the drive to develop new treatments for diseases or improve bioproduction processes, are key motivations. As a result, science is edging closer to creating synthetic bacteria, making the prospect of producing mirror bacteria increasingly realistic.

Mirror bacteria could potentially bypass the immune systems of humans, animals, and plants, leading to uncontrolled and deadly infections. Scientists are concerned that mirror bacteria might be impossible to contain and that existing antibiotics would offer insufficient protection.

A recent report has called for a global discussion on mirror bacteria. While mirror molecules are a focus of intense research, researchers are emphasizing the significant dangers that mirror bacteria could pose. They argue that compelling evidence is needed to demonstrate that such life forms do not present extraordinary risks before research in this area progresses. Experts further suggest that research aimed at creating mirror bacteria should be temporarily suspended, and they are calling for the discontinuation of financial support for this work.

The report exemplifies responsible research and innovation. Additionally, a call has been made in Science for open debate regarding the development of mirror organisms, alongside an emphasis on identifying the positive applications of mirror chemistry in biological systems—potentially within a limited and strictly regulated context. The discussion highlights the importance of carefully weighing scientific advancements against potential risks.

Technical Report on Mirror Bacteria: Feasibility and Risks (https://purl.stanford.edu/cv716pj4036)
Confronting risks of mirror life - Broad discussion is needed to chart a path forward (https://doi.org/10.1126/science.ads9158)